ACS Nano主編與生物材料牛人R. Langer的對話

2016-10-10新聞資訊

R. Langer


Robert S. Langer is one of 14 Institute Professors (the highest honor awarded to a faculty member) at the Massachusetts Institute of Technology (MIT).  Dr. Langer has written over 1,000 articles.  He also has more than 600 issued or pending patents worldwide. Dr. Langer’s patents have been licensed or sublicensed to over 200 pharmaceutical, chemical, biotechnology and medical device companies. He is the most cited engineer in history.
  
     He served as a member of the United States Food and Drug Administration’s SCIENCE Board, the FDA’s highest advisory board, from 1995 -- 2002 and as its Chairman from 1999-2002.
     Dr. Langer has received over 160 major awards including the 2006 United States National Medal of Science; the Charles Stark Draper Prize, considered the equivalent of the Nobel Prize for engineers and the 2008 Millennium Prize, the world’s largest technology prize.  He is the also the only engineer to receive the Gairdner Foundation International Award; 72 recipients of this award have subsequently received a Nobel Prize.  Among numerous other awards Langer has received are the Dickson Prize for Science (2002), Heinz Award for Technology, Economy and Employment (2003), the Harvey Prize (2003), the John Fritz Award (2003) (given previously to inventors such as Thomas Edison and Orville Wright), the General Motors Kettering Prize for Cancer Research (2004), the Dan David Prize in Materials Science (2005), the Albany Medical Center Prize in Medicine and Biomedical Research (2005), the largest prize in the U.S. for medical research, induction into the National Inventors Hall of Fame (2006), the Max Planck Research Award (2008) and the Prince of Asturias Award for Technical and Scientific Research (2008).  In 1998, he received the Lemelson-MIT prize, the world’s largest prize for invention for being “one of history’s most prolific inventors in medicine.”  In 1989 Dr. Langer was elected to the Institute of Medicine of the National Academy of Sciences, and in 1992 he was elected to both the National Academy of Engineering and to the National Academy of Sciences.  He is one of very few people ever elected to all three United States National Academies and the youngest in history (at age 43) to ever receive this distinction.
      Forbes Magazine (1999) and Bio World (1990) have named Dr. Langer as one of the 25 most important individuals in biotechnology in the world.  Discover Magazine (2002) named him as one of the 20 most important people in this area.  Forbes Magazine (2002) selected Dr. Langer as one of the 15 innovators world wide who will reinvent our future.  Time Magazine and CNN (2001) named Dr. Langer as one of the 100 most important people in America and one of the 18 top people in science or medicine in America (America’s Best).  Parade Magazine (2004) selected Dr. Langer as one of 6 “Heroes whose research may save your life.”  Dr. Langer has received honorary doctorates from Yale University, the ETH (Switzerland), the Technion (Israel), the Hebrew University of Jerusalem (Israel), the Universite Catholique de Louvain (Belgium), the University of Liverpool (England), the University of Nottingham (England), Albany Medical College, the Pennsylvania State University, Northwestern University and Uppsala University (Sweden).  He received his Bachelor’s Degree from Cornell University in 1970 and his Sc.D. from the Massachusetts Institute of Technology in 1974, both in Chemical Engineering.

 

羅伯特·S·蘭格(Robert S. Langer):生於1948年8月29日出生於紐約州奧爾巴尼,美國麻省理工學院教授。他是前化學和生物醫學工程“Germeshausen教授”,並且一直活躍在MIT的化學工程係和生物工程係。他還是哈佛-MIT健康科學技術分部(Harvard-MIT Division of Health Sciences and Technology)的一名教員。

他在生物技術領域,尤其是藥物輸送係統和組織工程領域享有很高的聲望。他在麻省理工的實驗室是世界最大的生物醫學工程實驗室,每年大約能獲得600萬美元的研究資助,實驗室的研究人員已經超過100名。

他對醫學和新出現的生物技術領域的貢獻已經得到全世界的高度認可和尊重。他被認為是許多新技術的先鋒開拓者,其中包括透皮給藥係統(transdermal delivery systems,即貼布)。這個係統能夠將藥物或身體的提取分析物以不需要注射或其他入侵方法的方式穿過皮膚。他和他實驗室的研究人員還在組織工程學領域取得了一些重要的進展,例如創造出血管工程肌肉組織(vascularized engineered musle tissue)和經改造的血管。

他持有超過550項已經通過申請或待審的專利,發表了超過900篇科學論文。他積極創業,先後參與創建了超過20個公司。蘭格曾獲得多個獎項,包括Charles Stark Draper獎、Lemelson-MIT獎和Albany醫學中心醫學與生物醫學研究大獎。此外,他還是當選美國三大科學院院士(美國科學院、美國工程院和醫學院)年紀最輕(43歲時)的人。

他還預測用新型生物材料製造的醫療器械也即將誕生。目前使用的大多數生物材料都是用於普通消費品生產的標準材料。比如,人工心髒所用的材料原來用於製造女士腰帶。有些豐胸材料曾經被用作床墊填充物。

獲獎成就:組織工程學和再生醫學的先驅研究

百科:組織工程學是由美國國家科學基金委員會於1987年正式提出和確定的,是應用細胞生物學、生物材料和工程學的原理,研究開發用於修複或改善人體病損組織或器官的結構、功能的生物活性替代物的一門科學。

再生醫學是通過研究機體的正常組織特征與功能、創傷修複與再生機製及幹細胞分化機理,尋找有效的生物治療方法,促進機體自我修複與再生,或構建新的組織與器官,以改善或恢複損傷組織和器官的功能的科學。